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Werner syndrome (WS) is a rare autosomal recessive disorder characterized by premature aging (von Kobe, et al., 2003). It is named after the German physician Carl W. Otto Werner (1879-1936), who first described the syndrome as part of his doctoral thesis in 1904. WS is caused by mutations in the RecQ family of helicase which are encoded by chromosome 8p by the WRN gene (Moser, et al., 1999). The mutations truncate the WRN protein with a loss of …

…was actually a gene which controlled senescence and he was right. He concluded that WS gene is a counter that modulates the frequency at which cells in culture leave the cell cycle (Faragher, et al., 1993).Still, there is much more research to be done to understand all aspects of the gene. Kyng's experiment focused mainly on the types of genes which were affected, but more research is needed before his findings could be considered definite.